Greene Science

We strive for overall product quality and satisfaction from our entire community, but we also aim toward total compliance and transparency of our products and brand. Check the details below for a multitude of scientific and technical information about our products!

*None of this information has been approved by the Food and Drug Administration.

The Entourage Effect

The Entourage Effect - Flavonoids, Cannabinoids, Terpenes

The entourage effect is a proposed mechanism by which hemp compounds other than THC act synergistically with each other to modulate the overall effect of the plant. Essentially, cannabinoids and terpenes potentially work together for greater overall health benefits than simply CBD on its own. The entourage effect is the name given to the phenomenon produced by the combined interaction of cannabinoids, terpenes, flavonoids and fatty acids. It is the effect of all the compounds and cannabinoids working in unison, rather than one or two working in isolation.

It seems that people can maintain their healthy lifestyles more easily with products that contain multiple cannabinoids, compared to those containing single isolated compounds and cannabinoids. This is why whole plant, or full spectrum is often favored, and why we stay away from CBD-only in our products. For example, research has suggested that CBD and CBG cannabinoids may be able to work in tandem to inhibit the bacterial staph infection MRSA (Source: Leafly). Furthermore, A 2010 study showed the potential positive efficacy of the entourage effect on cancer patients dealing with chronic pain. Bottom line: the myriad of cannabinoids and terpenes naturally found in all of Greene’s Reserve hemp products makes us the superior choice over CBD-isolate competitors.

Bisabolol

Bisabolol
A terpene with a warm floral fragrance similar to honey, apples, and chamomile. Bisabolol is known for its proported benefits that include antimicrobial, anti-inflammatory, antioxidant, and anti-cancer properties.

Hexahydrothymol

Hexahydrothymol
Also known as menthol, this terpene has been used as a topical analgesic, but has the possibility of relieving minor aches and pains. Known for its signature scent, we strive to also take advantage of the potential health benefits of menthol.

Cannabinoids

Cannabinoids are naturally occurring compounds found in hemp and cannabis plants. According to the NIH, these plants contain up to 540 chemical substances that may be beneficial for human consumption. Current research suggests that there may be over 150 known cannabinoids naturally found in hemp.

Greene's Reserve products contain:

CBD

CBD Chemical compound
One of the best-known cannabinoids found in hemp, cannabidiol (CBD) has helped spark a cultural revolution and attitude shift toward hemp and cannabis as a whole. A non-psychoactive compound, the CBD revolution has been credited with health benefits for decades. Although not evaluated or approved by the FDA, CBD has the potential for pain relief, reduction of depression and anxiety, and the propensity to alleviate cancer-related symptoms. In addition, further studies are attempting to show CBD’s potential as a neuroprotective against such as epilepsy, Alzheimer’s disease, Parkinson’s, and multiple sclerosis.

CBG

Cannabigerol works by binding to both the CB1 & CB2 receptors of the endocannabinoid system. Typically, lesser quantities of CBG are found in the hemp plant when compared to others. Like CBD, CBG may help with pain relief without the intoxicating effects of THC. The human body’s built-in works to keep the body in its balanced state of homeostasis. While there are in general the endocannabinoid system performs different functions specific to each area of the body. For example, at an injury site, the ECS can help regulate immune cells to limit inflammation.

CBDA

CBDA chemical compound
CBDA is simply short for cannabidiolic acid, and is essentially a precursor to CBD. Unlike other cannabinoids, CBDA does not bind to our endocannabinoid receptors. Instead, CBDA has been shown in studies to deactivate enzymes associated with inflammation to reduce overall pain, while boosting recovery.

CBC

CBC molecule
Cannabichromene, or CBC, is also non-intoxicating (much like CBD). Unlike other cannabinoids, CBC does not bind to cannabinoid receptors, but rather the transient receptor TRPV1- which is linked to pain perception. Some studies have also linked CBC as a potential cancer fighter.

CBDV

CBDV chemical compound
Cannabidivarin (CBDV) is a non-psychoactive cannabinoid that may have similar effects of CBD. CBDV may reduce inflammation, nausea, and even reduce the occurrence and frequency of seizures. Much of the research around CBDV has centered around its effect on seizures. GW Pharmaceuticals, which developed the first FDA-approved CBD drug called E, is actively developing

CBN

CBN chemical compound
Cannabinol (CBN) comes from the chemical breakdown of the THC cannabinoid. It is technically mildly psychoactive, but generally produces no high the way THC would. Although CBN is currently less researched than CBD, precursory information suggests that CBN may help in getting to sleep and staying asleep. In addition, it is suggested that CBN may have similar qualities of pain reduction, inflammatory treatment, neuroprotective events, and more.

THC

THC Molecule

Greene’s Reserve hemp is farmed and milled specifically to have very low THC concentrations, while retaining the benefits of all other natural cannabinoids and terpenes. Tetrahydrocannabinol (THC) is the principal psychoactive constituent in cannabis, responsible for the “high” feeling associated with marijuana. Hemp, however, also contains very small amounts of this compound (up to 0.3% legally at the federal level). The highest THC concentration we have seen in laboratory analysis has been 0.04%, an amount that can be found in varieties of wild lettuce. See third-party laboratory testing results HERE. Also, check out our FAQ for more information on how this affects drug testing.

Terpenes

Terpenes are simply aromatic compounds that are found in many plants - not just hemp and cannabis. Hemp plants contain very high concentrations of terpenes, and are responsible for characteristic scents and effects of each plant based partly upon terpene makeup.

Greene's Reserve products contain:

Cedrol (or Cedrene)

Cedrol
Cedrol is a musky terpene that is present in juniper and other essential conifer oils, as well as in some herbs, to include hemp. The floral, woody aromas have made it a staple of hygiene and fragrance products. Effects suggested potential as an antioxidant and anti-inflammatory, along with other beneficial effects. These compounds have been found to have antiseptic, anti-inflammatory, antispasmodic, tonic, astringent, diuretic, sedative, insecticidal, and antifungal activities.

Caryophyllene

Caryophyllene
Caryophyllene is an earthy and spicy terpene that is also present in black pepper, basil, and oregano. Binding to the CB-1 receptor, it is speculated that Caryophyllene can activate the endocannabinoid system and possibly provide anti-inflammatory effects.

Limonene

Limonene
Like its name suggests, limonene is an aromatic terpene that is known for producing citrus-like scents in fruits as well as in the hemp plant. Today, this terpene is being investigated for its antioxidant, anti-inflammatory, and chemo preventive effects.

Guaiol

Guaiol
Sometimes referred to as champacol, Guaiol is unique as water-based, compared to other terpenes that are mostly oil-based. Producing a woody or pine smell, Guaiol is being researched as an effective anti-inflammatory.